Vibrational spectroscopy is sensitive to molecular structure and dynamics. This has made it an attractive candidate as a microscopic contrast agent. We are developing wide-field, femtosecond infrared spectroscopic imaging methods that provide temporal and spatial resolution. Using the Ge AOM pulse shaper pioneered by the Zanni group and a state-of-the-art IR focal plane array (FPA), we have successfully collected FTIR images of metal carbonyls absorbed in polystyrene beads. This demonstrates that femtosecond IR laser sources are viable candidates for new infrared imaging methods and can spatially resolve distinct chemical species. New experiments are underway to combine 2D IR spectroscopy and wide-field infrared imaging.
- Selected Publications
- Ostrander, J. S.; Serrano, A. L.; Ghosh, A.; Zanni, M. T. Spatially Resolved Two-Dimensional Infrared Spectroscopy via Wide-Field Microscopy. ACS Photonics 2016, 3, 1315–1323.