Recent Papers

Shot-to-shot 2D IR spectroscopy at 100 kHz using a Yb laser and custom-designed electronics.

Farrell KM, Ostrander JS, Jones AC, Yakami BR, Dicke SS,  Middleton CT, Hamm P, Zanni MT. Opt Express (2020).





Providing Time to Transfer: Longer Lifetimes Lead to Improved Energy Transfer in Films of Semiconducting Carbon Nanotubes

Flach JT,Wang J, Arnold MS, Zanni MT. J.Phys. Chem. Lett. (2020)



A Different hIAPP Polymorph Is Observed in Human Serum Than in Aqueous Buffer: Demonstration of a New Method for Studying Amyloid Fibril Structure Using Infrared Spectroscopy.

Fields CR, Dicke SS, Petti MK, Zanni MT, Lomont JP. J.Phys. Chem. Lett. (2020)




Thermal Annealing of Singlet Fission Microcrystals Reveals the Benefits of Charge Transfer Couplings and Slip-Stacked Packing

Armstrong ZT, Bohlmann Kunz M, Jones AC, Zanni MT. J. Phys. Chem. C (2020).





A Proposed Method to Obtain Surface Specificity with Pump-Probe and 2D Spectroscopies

Petti MK, Ostrander JS, Birdsall ER, Bohlmann Kunz M, Armstrong ZT, Alperstein AM, Zanni MT. J. Phys. Chem. A (2020).



Dual spectral phase and diffraction angle compensation of a broadband AOM 4-f pulse-shaper for ultrafast spectroscopy

Jones AC, Bohlmann Kunz M, Tigges-Green I, and Zanni MT. J. Opt. Express (2019).







Multidimensional Spectroscopy on the Microscale: Development of a Multimodal Imaging System Incorporating 2D White-Light Spectroscopy, Broadband Transient Absorption, and Atomic Force Microscopy

Jones AC, Kearns NM, Bohlmann Kunz M, Flach JT, and Zanni MT. J. Phys. Chem. A (2019).


Impacts of non-equilibrium molecular packings on singlet fission in microcrystals observed using 2D white-light microscopy

Jones AC, Kearns NM, Ho JJ, Flach JT, and Zanni MT. Nat. Chem. (2019).




Monolayer Sensitivity Enables a 2D IR spectroscopic Immuno-biosensor for Studying Protein Structures: Application to Amyloid Polymorphs

Ostrander JS, Lomont JP, Rich KL, Saraswat V, Feingold BR, Petti MK, Birdsall ER, Arnold MS, and Zanni MT. J. Phys. Chem. Lett. (2019), 10, 14, 3836-3962.  



Two-Dimensional Whit-Light Spectroscopy Using Supercontinuum from an All-Normal Dispersion Photonic Crystal Fiber Pumped by a 70 MHz Yb Fiber Oscillator

                                                                                    Kearns NM, Jones AC, Bohlmann Kunz M, Allen RT, Flach JT, and  Zanni MT. J. Phys. Chem. A.                                                                                        

Amyloid found in human cataracts with two-dimensional infrared spectroscopy

Alperstein AM, Ostrander JS, Zhang  TO, and  Zanni MT. Proc. Natl. Acad. Sci. USA. (2019)  

Enhancing the signal strength of surface sensitive 2D IR spectroscopy

Petti MK, Ostrander JS, Saraswat V, Birdsall ER, Rich KL, Lomont JP, Arnold MS, and  Zanni MT.                                                                                     J. Chem. Phys. (2019), 150, 024707.

Two-Dimensional Electronic Spectroscopy Reveals Excitation Energy-Dependent State Mixing During Singlet Fission in a Terrylenediimide Dimer

Mandal A, Chen M, Foszcz ED, Schultz JD, Kearns NM, Young RM,  Zanni MT, and Wasielewski MR, JACS (2018), 140 (51), pp 17907–17914.

Structural Polymorphs Suggest Competing Pathways for the Formation of Amyloid Fibrils That Diverge from a Common Intermediate Species

Buchanan LE, Maj M, Dunkelberger EB, Cheng PN, Nowick JS and Zanni MT, Biochemistry (2018), 57 (46), pp 6470–6478.


Heterogeneous Amyloid β-Sheet Polymorphs Identified on Hydrogen Bond Promoting Surfaces Using 2D SFG Spectroscopy

Ho JJ, Ghosh A, Zhang TO and Zanni M T, Journal of Physical Chemistry A (2018), 122, 1270-1282



Spectroscopic Signature for Stable β-Amyloid Fibrils verus β-sheet-Rich Oligomers

Lomont JP, Rich KL, Maj M, Ho JJ, Ostrander JS and Zanni M T, Journal of Physical Chemistry B (2018), 122, 144-153



Two-Dimensional Spectroscopy Is Being Used to Address Core Scientific Questions in Biology and Materials Science

Petti MK, Lomont JP, Maj M and Zanni M T, Journal of Physical Chemistry B (2018), 122, 1771-178


Amyloid β-Sheet Secondary Structure Identified in UV-Induced Cataracts of Porcine Lenses using 2D IR Spectroscopy

Zhang TO, Alperstein AM and Zanni M T, Journal of Molecular Biology (2017), 429, 1705-1721



Broadband 2D electronic spectrometer using white light and pulse shaping: noise and signal evaluation at 1 and 100 kHz

Kearns NM, Mehlenbacher RD, Jones AC and Zanni M T, Optics Express (2017), 25, 7869-7883



Site-specific detection of protein secondary structure using 2D IR dihedral indexing: a proposed assembly mechanism of oligomeric hIAPP

Maj M, Lomont JP, Rich KL, Alperstein AM and Zanni M T, Chemical Science (2018), 9, 463-474


Energy Transfer Between Coherently Delocalized States in Thin Films of the Explosive Pentaerythritol Tetranitrate (PETN) Revealed by Two-Dimensional Infrared Spectroscopy

Ostrander JS, Knepper R, Tappan AS, Kay JJ, Zanni M T and Farrow DA, Journal of Physical Chemistry B (2017), 121, 6, 1352-1361


A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP

Serrano AL, Lomont JP, Tu L-H, Raleigh DP and Zanni M T, Journal of the American Chemical Society (2017), 139, 46, 16748-16758


GXXXG‐Mediated Parallel and Antiparallel Dimerization of Transmembrane Helices and Its Inhibition by Cholesterol: Single‐Pair FRET and 2D IR Studies

Yano Y, Kondo K, Watanabe Y, Zhang TO, Ho J-J, Oishi S, Fujii N, Zanni M T and Matsuzaki K, Angewandte Chemie (2017), 129, 7, 1782-1785


Not All β-Sheets Are the Same: Amyloid Infrared Spectra, Transition Dipole Strengths, and Couplings Investigated by 2D IR Spectroscopy

Lomont JP, Ostrander JS, Ho J-J, Petti MK and Zanni M T, Journal of Physical Chemistry B (2017), 121, 38, 8935-8945


Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy

Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI and Zanni M T, Journal of the American Chemical Society (2017), 139, 26, 8837-8845